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The 8 Best Men’s Fall Shoe Styles For 2024
The 8 Best Men’s Fall Shoe Styles For 2024
New Balance 1906R Cordura Trail Shoes
New Balance 1906R Cordura Trail Shoes
How Jeremy Fragrance Defeated Dating Apps
How Jeremy Fragrance Defeated Dating Apps
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Aug , 2024
Mayo Clinic pioneers use of pulsed field ablation to treat atrial fibrillation
Tag: Preclinical

Mayo Clinic pioneers use of pulsed field ablation to treat atrial fibrillation

Cardiologists in Mayo Clinic’s Heart Rhythm Clinic are using a new innovative energy source to safely and successfully treat a common type of heart arrhythmia. The therapy, called pulsed field ablation (PFA), has received Food and Drug Administration (FDA) approval and represents a significant milestone in treating atrial fibrillation (AFib). The irregular and often very […]

8

Aug , 2024
Review of fasting-mimicking diets in cancer treatment
Tag: Preclinical

Review of fasting-mimicking diets in cancer treatment

In a recent review published in Cell Metabolism, researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy. Study: Cyclic fasting-mimicking diet in cancer treatment: Preclinical and clinical evidence. Image Credit: vetre/Shutterstock.com FMDs have anticancer properties that potentiate conventional therapies and protect normal tissues. In phase 1/2 clinical studies, cyclic FMD […]

21

Jul , 2024
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
Tag: Preclinical

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania’s Perelman School of Medicine […]

21

Jul , 2024
Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei
Tag: Preclinical

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Published in Clinical Cancer Research, results of a preclinical study led by investigators of the Vall d’Hebron Institute of Oncology’s (VHIO) Stem Cells and Cancer Group, headed by Héctor G. Palmer, pave the way for systemic targeted therapy in patients with pseudomyxoma peritonei, a rare form of cancer with very few therapeutic options available. This […]

12

Jul , 2024
CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma
Tag: Preclinical

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven’t experienced improvement with chemotherapy treatments. But if this CAR-T treatment fails, or the cancer returns yet again -; as happens in approximately half of […]

21

Jun , 2024
cardiovascular disease and environmental factors
Tag: Preclinical

cardiovascular disease and environmental factors

A recent study published in JAAC CardioOncology reviewed preclinical and epidemiologic evidence linking air pollution to cardio-oncology. Study: Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus: JACC: CardioOncology State-of-the-Art Review. Image Credit: Inside Creative House/Shutterstock.com Background Cancer therapies have substantially improved the survival rate of patients. However, chronic health conditions have emerged as the lifespan of cancer patients increased. […]

20

Jun , 2024
Yeast-fermented bread shows promise in preventing asthma symptoms
Tag: Preclinical

Yeast-fermented bread shows promise in preventing asthma symptoms

A recent study published in Current Developments in Nutrition investigated the effects of a functional bread fermented with yeast (Saccharomyces cerevisiae) in asthma prevention. ​​​​​​​Study: A Functional Bread Fermented with Saccharomyces cerevisiae UFMG A-905 Prevents Allergic Asthma in Mice. Image Credit: Sunshine Seeds/Shutterstock.com Background Asthma is a complex, heterogeneous disease characterized by airway inflammation, remodeling, and hyper-responsiveness. Asthma prevalence […]

23

May , 2024
Insilico Medicine’s leadership to address key challenges in AI drug discovery at BIO Convention
Tag: Preclinical

Insilico Medicine’s leadership to address key challenges in AI drug discovery at BIO Convention

Leadership from clinical stage artificial intelligence (AI)-powered drug discovery company Insilico Medicine (“Insilico”) will attend the BIO International Convention in San Diego June 3-6 and present on key issues facing AI drug discovery. Company leadership, including Chief Business Officer Michelle Chen, PhD; Keith Mikule, PhD, Vice President for Business Development; Jue Wang, PhD, Head of Business […]

21

May , 2024
ERS Genomics and IRBM sign CRISPR/Cas9 license agreement
Tag: Preclinical

ERS Genomics and IRBM sign CRISPR/Cas9 license agreement

ERS Genomics Limited (‘ERS’), the CRISPR licensing Company, and IRBM, a leader in the field of drug discovery, today announced a non-exclusive CRISPR/Cas9 license agreement. The agreement grants IRBM access to ERS’ CRISPR/Cas9 patent portfolio. IRBM is a drug discovery CRO with expertise ranging from target validation and hit finding to preclinical candidate nomination across […]

3

May , 2024
Gyros Protein Technologies introduces Gyrolab Generic Rodent ADA Kit Reagents to support preclinical immunogenicity assessment
Tag: Preclinical

Gyros Protein Technologies introduces Gyrolab Generic Rodent ADA Kit Reagents to support preclinical immunogenicity assessment

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and a leading provider of peptide synthesizers and reagents, today announced the introduction of Gyrolab® Generic Rodent Anti-Drug Antibody (ADA) Kit Reagents for the detection of circulating immune complexes of human IgG with rodent anti-human IgG. Validated for use with mouse and rat samples, the Kit […]
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