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Arne’s Big Move: From Digital Darling to Real-World Power Player
Arne’s Big Move: From Digital Darling to Real-World Power Player
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
An Icon Reimagined: The Uncompromising Style of the &SONS McQueen Boots
An Icon Reimagined: The Uncompromising Style of the &SONS McQueen Boots
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18

Jul , 2024
Drinking coffee daily linked to decreased PCOS risk
Tag: Phenotype

Drinking coffee daily linked to decreased PCOS risk

A recent study published in the journal Nutrients investigates the association between coffee consumption and polycystic ovarian syndrome (PCOS) in women. Study: Association between Coffee Consumption and Polycystic Ovary Syndrome: An Exploratory Case–Control Study. Image Credit: Daria Aleshina / Shutterstock.com PCOS: Symptoms, Prevalence and Treatment Women with PCOS often suffer from dysfunctional gonadotropin hormonal synthesis that […]

13

Jul , 2024
New 3D model sheds light on amyloid-beta’s impact
Tag: Phenotype

New 3D model sheds light on amyloid-beta’s impact

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have unveiled a pioneering study shedding light on the intricate mechanisms underlying Alzheimer’s disease (AD). The study, titled “Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype,” represents a significant leap forward in understanding the interplay between amyloid-like structures and neuronal cells. Led by […]

5

Jul , 2024
More than 1,000 small changes in DNA identified that influence age of first period
Tag: Phenotype

More than 1,000 small changes in DNA identified that influence age of first period

In a recent study published in Nature Genetics, researchers examined nearly 800,000 women’s deoxyribonucleic acid (DNA) to explore puberty timing complexities. They identified signals related to menarche timing and investigated their influence on puberty onset. Study: Understanding the genetic complexity of puberty timing across the allele frequency spectrum. Image Credit: CGN089/Shutterstock.com Background Age at menarche […]

28

May , 2024
Understanding the link between EBV-infected B cells and multiple sclerosis
Tag: Phenotype

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute’s Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells […]

11

May , 2024
Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy
Tag: Phenotype

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy.” In this new editorial, researcher Ioannis A. Voutsadakis from Sault Area Hospital and Northern Ontario School of Medicine discusses tumor mutation burden (TMB)-;a novel clinical biomarker for prediction of checkpoint inhibitor immunotherapy […]

21

Apr , 2024
Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson’s progression
Tag: Phenotype

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson’s progression

In a recent study published in the journal Nature Medicine, a large, international team of researchers conducted an exploratory analysis to evaluate whether the monoclonal antibody prasinezumab, which had previously been observed to be effective in slowing the progression of motor-associated signs of Parkinson’s disease, did indeed show benefits in subgroups of Parkinson’s disease patients […]

16

Oct , 2023
Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines
Tag: Phenotype

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

A recent study published in the journal Science discussed variant-adapted boosters for coronavirus disease 2019 (COVID-19). Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have decreased the burden of the COVID-19 pandemic. Nevertheless, the waning of neutralizing antibodies (nAbs) and the emergence of variants of concern (VOCs) have reduced the efficacy of vaccines, prompting […]

26

Jul , 2023
Cancer patients see significant fall in Covid-related hospitalizations, mortality following vaccine rollout
Tag: Phenotype

Cancer patients see significant fall in Covid-related hospitalizations, mortality following vaccine rollout

Cancer patients saw a significant fall in Covid-related hospitalizations and mortality following the rollout of vaccines in the first panoramic study of its kind. The research published in Scientific Reports today (Tuesday 25 July) looked at the impact of the global pandemic on case-outcome rates for cancer patients across a 21-month period from November 2020 […]