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10

Jul , 2024
Blocking nidogen-2 enhances chemotherapy efficacy in pancreatic cancer
Tag: Metastasis

Blocking nidogen-2 enhances chemotherapy efficacy in pancreatic cancer

Researchers at the Garvan Institute of Medical Research have identified a potential new therapeutic target for pancreatic cancer, one of the most lethal cancer types with limited treatment options. Published in the journal Science Advances, the study shows that blocking the molecule nidogen-2 enhanced the effectiveness of chemotherapy and reduced the cancer’s spread in mouse […]

13

May , 2024
Plant virus-derived treatment shows promise against metastatic cancers
Tag: Metastasis

Plant virus-derived treatment shows promise against metastatic cancers

An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus-;a virus that infects black-eyed pea plants-;showed remarkable success in improving survival rates […]

13

Apr , 2024
New microfluidic device improves the separation of tumor cells and clusters from malignant effusions
Tag: Metastasis

New microfluidic device improves the separation of tumor cells and clusters from malignant effusions

Researchers have unveiled a microfluidic device that significantly improves the separation of tumor cells and clusters from malignant effusions. This novel technology promises to advance the diagnosis and treatment monitoring of cancer by enabling the high-throughput, continuous-flow ternary separation of single tumor cells, tumor cell clusters, and white blood cells (WBCs) from clinical pleural or […]

12

Mar , 2024
New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread
Tag: Metastasis

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique […]

8

Sep , 2023
Capture and release of tumor cells using a bioelectronic device
Tag: Metastasis

Capture and release of tumor cells using a bioelectronic device

In the book entitled Microfluidic Systems for Cancer Diagnosis, the UPV/EHU’s Microfluidics Cluster group describes the process for building a bioelectronic device consisting of gold electrodes coated with a smart polymer capable of capturing and releasing cells in a non-invasive, controllable way while monitoring the processes using conventional electrical measurements. These are the first steps […]

24

Aug , 2023
Study shows how cancer can selfishly hijack a helpful immune pathway to spread
Tag: Metastasis

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway. Usually, activation of this key immune pathway -; called the STING pathway -; triggers a strong […]

23

Aug , 2023
New calculator predicts risk of early recurrence in patients with hepatocellular carcinoma
Tag: Metastasis

New calculator predicts risk of early recurrence in patients with hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer of the liver and the fourth leading cause of cancer-related mortality worldwide, with China accounting for over half of the global annual cases and deaths. Hepatectomy is the standard curative-intent treatment option for appropriately selected patients with localized HCC. However, the high postoperative recurrence rate causes […]

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