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Chris Eubank Jr Just Turned a Fight Presser Into a Louis Vuitton Runway
Chris Eubank Jr Just Turned a Fight Presser Into a Louis Vuitton Runway
6 of our favourite outerwear essentials from Sendero
6 of our favourite outerwear essentials from Sendero
5 Best All-Black Sneakers for Men: Stone Cold Style in 2025
5 Best All-Black Sneakers for Men: Stone Cold Style in 2025
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28

Jul , 2024
Breakthrough therapy heals spinal cord injuries
Tag: Gene Expression

Breakthrough therapy heals spinal cord injuries

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving “dancing molecules,” to repair tissues and reverse paralysis after severe spinal cord injuries. Now, the same research group has applied the therapeutic strategy to damaged human cartilage cells. In the new study, the treatment activated the gene expression necessary to regenerate cartilage […]

28

May , 2024
Understanding the link between EBV-infected B cells and multiple sclerosis
Tag: Gene Expression

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute’s Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells […]

5

Mar , 2024
New method simplifies production of limb progenitor cells from fibroblasts
Tag: Gene Expression

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or “reprogram” fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells. Publishing in Developmental Cell, the researchers’ findings have enhanced our understanding of limb development and have set […]

3

Mar , 2024
Exploring the epigenetic impact of smoking across racial and ethnic groups
Tag: Gene Expression

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses. But the link between epigenetics (the study of mechanisms that impact gene expression) and smoking is not fully understood, especially in terms of differences across racial and ethnic groups. We know that smoking affects […]

11

Jan , 2024
Revolutionary blood test monitors gene expression dynamics in the brain
Tag: Gene Expression

Revolutionary blood test monitors gene expression dynamics in the brain

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels. While this particular anatomical setup protects it from outside invaders, it also makes it difficult for researchers to study how specific genes are expressed ⎯ and how such changes in gene expression may […]

5

Jan , 2024
How miRNAs influence health and disease
Tag: Gene Expression

How miRNAs influence health and disease

In a recent study published in Nutrients, researchers reviewed the role of dietary microRNAs (miRNAs) in health and disease. Study: Dietary Epigenetic Modulators: Unravelling the Still-Controversial Benefits of miRNAs in Nutrition and Disease. Image Credit: ART-ur/Shutterstock.com Background Diet is one of the lifestyle factors with a substantial impact on health. Unhealthy diets have been responsible for several […]

6

Dec , 2023
HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors
Tag: Gene Expression

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar tissue, that surrounds most pancreatic tumors and makes it hard for drugs to access and destroy the cancer cells. Now, […]

10

Sep , 2023
Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal
Tag: Gene Expression

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Tiziana Life Sciences Ltd. (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced acceptance of a publication, “Nasal Administration of anti-CD3 monoclonal antibody (mAb) ameliorates disease in a mouse model of Alzheimer’s disease”, in the preeminent journal, Proceedings of the National Academy of Sciences (PNAS), that […]

26

Aug , 2023
Study could explain why astronauts’ T cells become less effective at fighting infection
Tag: Gene Expression

Study could explain why astronauts’ T cells become less effective at fighting infection

A new study led by researchers at Karolinska Institutet in Sweden has examined how T cells of the immune system are affected by weightlessness. The results, which are published in the journal Science Advances, could explain why astronauts’ T cells become less active and less effective at fighting infection. The next steps in the exploration […]

19

Aug , 2023
RARα receptor plays unexpected role in T cell activation
Tag: Gene Expression

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, but it also now appears to operate outside the […]
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