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All The Best Bargains from The Huckberry Cyber Monday Sale
All The Best Bargains from The Huckberry Cyber Monday Sale
11 Best Travel Wallets for Men 2025
11 Best Travel Wallets for Men 2025
20 Best Cargo Pants For Men in 2025
20 Best Cargo Pants For Men in 2025
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23

May , 2024
Insilico Medicine’s leadership to address key challenges in AI drug discovery at BIO Convention
Tag: Fibrosis

Insilico Medicine’s leadership to address key challenges in AI drug discovery at BIO Convention

Leadership from clinical stage artificial intelligence (AI)-powered drug discovery company Insilico Medicine (“Insilico”) will attend the BIO International Convention in San Diego June 3-6 and present on key issues facing AI drug discovery. Company leadership, including Chief Business Officer Michelle Chen, PhD; Keith Mikule, PhD, Vice President for Business Development; Jue Wang, PhD, Head of Business […]

27

Apr , 2024
Human mini-lungs mimic animal response to nanomaterials
Tag: Fibrosis

Human mini-lungs mimic animal response to nanomaterials

Human mini-lungs grown by University of Manchester scientists can mimic the response of animals when exposed to certain nanomaterials. The study at the University’s NanoCell Biology Lab at the Centre for Nanotechnology in Medicine is published in the influential journal Nano Today. Though not expected to replace animal models completely, human organoids could soon lead to […]

17

Apr , 2024
Vaccines targeting chronic diseases show promise in combatting age-related conditions
Tag: Fibrosis

Vaccines targeting chronic diseases show promise in combatting age-related conditions

In a recent review published in Nature Aging, researchers explored vaccine-based therapeutics for age-related disorders. Study: Targeting aging and age-related diseases with vaccines. Image Credit: Ground Picture/Shutterstock.com Background Aging is a primary risk factor for chronic illnesses, marked by reduced physiological capabilities. Cell senescence, genomic instability, stem cell fatigue, and mitochondrial failure are characteristics. Aging also increases […]

10

Mar , 2024
New research identifies potential drug target to prevent kidney failure
Tag: Fibrosis

New research identifies potential drug target to prevent kidney failure

A new study found that retinoic acid receptors (RARa) in the proximal tubules of the kidney play a crucial role in limiting the damaging effects of kidney injury that often lead to kidney failure. Researchers from Weill Cornell Medicine have developed a preclinical model that showed a condition like chronic kidney disease develops when RARa […]

6

Dec , 2023
HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors
Tag: Fibrosis

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar tissue, that surrounds most pancreatic tumors and makes it hard for drugs to access and destroy the cancer cells. Now, […]

28

Sep , 2023
Examining the cardiac pathology in fatal cases of yellow fever
Tag: Fibrosis

Examining the cardiac pathology in fatal cases of yellow fever

In a recent study published in eBioMedicine, researchers examined the histopathological features and immunohistochemical and proteomic characteristics of yellow fever (YF)-related myocardial damage. Study: Understanding yellow fever-associated myocardial injury: an autopsy study. Image Credit: nechaevkon/Shutterstock.com Background Yellow fever is characterized by a hemorrhagic fever of viral etiology with significant morbidity prevalent in portions of Africa and South […]

9

Sep , 2023
Study could pave the way to new treatments for people with compromised immune systems
Tag: Fibrosis

Study could pave the way to new treatments for people with compromised immune systems

New research led by Queen’s University Belfast has made a breakthrough in the field of microbiology, which could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis. Image Credit: Queen’s University Belfast To conduct their study the researchers looked at the bacterium Achromobacter which can […]

9

Aug , 2023
Yale researchers create “humanized” liver in living mice to study chronic liver diseases
Tag: Fibrosis

Yale researchers create “humanized” liver in living mice to study chronic liver diseases

Yale researchers have created a functional “humanized” liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. The findings are published Aug. 9 in the journal Cell. Chronic liver diseases such as alcoholic […]

30

Jul , 2023
Newborn screening negatively effects short- and long-term health outcomes in infants with cystic fibrosis
Tag: Fibrosis

Newborn screening negatively effects short- and long-term health outcomes in infants with cystic fibrosis

The Journal of Pediatrics has published a manuscript by Stacey Martiniano, MD, pulmonary specialist at Children’s Hospital Colorado and associate professor of pediatrics at the University of Colorado. Dr. Martiniano was primary author on the study titled, Late Diagnosis in the Era of Universal Newborn Screening Negatively Effects Short- and Long-Term Growth and Health Outcomes […]

21

Jul , 2023
Extracellular vesicles may drive fibrosis in scleroderma
Tag: Fibrosis

Extracellular vesicles may drive fibrosis in scleroderma

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology. Characterized by stiff and hardening tissue known as fibrosis, systemic sclerosis – also known as scleroderma – can affect the skin as well as other organs. Most research has focused on […]
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