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Beyond the Pavement: The Uncompromising Lems Trail Thrasher
Beyond the Pavement: The Uncompromising Lems Trail Thrasher
10 of the best new hats from Sendero this month
10 of the best new hats from Sendero this month
Scott Galloway, Richard Reeves, Jed Diamond On The Future of Man Kind
Scott Galloway, Richard Reeves, Jed Diamond On The Future of Man Kind
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Apr , 2024
Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice
Tag: Fatty Liver

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells’ powerhouses, the mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse diet-induced obesity, fatty liver and diabetes in mice. Mitochondria are essential for human […]

20

Aug , 2023
Meta-analysis reports global prevalence of MAFLD of 38.8% in adults
Tag: Fatty Liver

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population. It is characterized by the accumulation of fat in the liver. It is often associated with other conditions, such as obesity, type 2 diabetes, and metabolic syndrome. The new definition of metabolic dysfunction-associated fatty liver […]

11

Aug , 2023
Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet
Tag: Fatty Liver

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway. Thus, this study provides clinical reference and theoretical basis for the application of glucokinase activator (GKA) in treating patients with type […]

9

Aug , 2023
Yale researchers create “humanized” liver in living mice to study chronic liver diseases
Tag: Fatty Liver

Yale researchers create “humanized” liver in living mice to study chronic liver diseases

Yale researchers have created a functional “humanized” liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. The findings are published Aug. 9 in the journal Cell. Chronic liver diseases such as alcoholic […]