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LANX Ribchester Boots: Your New Go-To for Tackling the Great Outdoors in Style
LANX Ribchester Boots: Your New Go-To for Tackling the Great Outdoors in Style
Arne’s Big Move: From Digital Darling to Real-World Power Player
Arne’s Big Move: From Digital Darling to Real-World Power Player
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
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Apr , 2024
Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice
Tag: Fatty Liver

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells’ powerhouses, the mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse diet-induced obesity, fatty liver and diabetes in mice. Mitochondria are essential for human […]

20

Aug , 2023
Meta-analysis reports global prevalence of MAFLD of 38.8% in adults
Tag: Fatty Liver

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population. It is characterized by the accumulation of fat in the liver. It is often associated with other conditions, such as obesity, type 2 diabetes, and metabolic syndrome. The new definition of metabolic dysfunction-associated fatty liver […]

11

Aug , 2023
Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet
Tag: Fatty Liver

Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway. Thus, this study provides clinical reference and theoretical basis for the application of glucokinase activator (GKA) in treating patients with type […]

9

Aug , 2023
Yale researchers create “humanized” liver in living mice to study chronic liver diseases
Tag: Fatty Liver

Yale researchers create “humanized” liver in living mice to study chronic liver diseases

Yale researchers have created a functional “humanized” liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. The findings are published Aug. 9 in the journal Cell. Chronic liver diseases such as alcoholic […]