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7

Jul , 2024
Breakthrough humanized mouse model offers new insights for immunotherapy development
Tag: Epigenetics

Breakthrough humanized mouse model offers new insights for immunotherapy development

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created a humanized mouse model with a human immune system and a human-like gut microbiome that is capable of mounting specific antibody responses. The scientists were led by Paolo […]

1

Jun , 2024
key to reducing heart disease and mortality through epigenetics
Tag: Epigenetics

key to reducing heart disease and mortality through epigenetics

In a recent study published in the Journal of the American Heart Association, researchers investigated whether Deoxyribonucleic Acid (DNA) methylation-based epigenetic age biomarkers mediate the associations between Life’s Essential 8 (LE8) score and risks of cardiovascular disease (CVD), CVD-specific mortality, and all-cause mortality. Study: Epigenetic Age Mediates the Association of Life’s Essential 8 With Cardiovascular Disease […]

3

Mar , 2024
Exploring the epigenetic impact of smoking across racial and ethnic groups
Tag: Epigenetics

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses. But the link between epigenetics (the study of mechanisms that impact gene expression) and smoking is not fully understood, especially in terms of differences across racial and ethnic groups. We know that smoking affects […]

29

Feb , 2024
PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases
Tag: Epigenetics

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University. This partnership will focus on ‘gene-based environmental biomarkers,’ known as epigenetic markers, for calculating risk scores for Alzheimer’s disease. Together with ALZmetrixTM, PharmaKure’s blood-based biomarker, this will increase the […]

28

Aug , 2023
A new understanding of the role of the NSL complex
Tag: Epigenetics

A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals. Abrogation of the NSL genes leads to the death of the organism, and this phenotype gives rise to this complex’s curious name. Max Planck researchers have now identified […]

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