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Why Levi’s 502 Regular Taper Feels Different Than It Sounds
Why Levi’s 502 Regular Taper Feels Different Than It Sounds
Escape Gym Groundhog Day: Why Your Training Needs Seasons
Escape Gym Groundhog Day: Why Your Training Needs Seasons
Imogene + Willie Galway Wool Sweater: A Masterclass in Irish Soul and American Grit
Imogene + Willie Galway Wool Sweater: A Masterclass in Irish Soul and American Grit
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May , 2024
Advanced techniques reveal plectasin’s velcro-like action against bacteria
Tag: Cell Wall

Advanced techniques reveal plectasin’s velcro-like action against bacteria

A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface comparable to how both sides of Velcro form a bond. A research team, led by structural biologist Markus Weingarth and biochemist Eefjan Breukink at Utrecht University, mapped how […]

6

Sep , 2023
a game-changing novel antibiotic with no resistance
Tag: Cell Wall

a game-changing novel antibiotic with no resistance

In a recent article published in the Cell Journal, researchers reported the discovery of a new antibiotic, clovibactin. Clovibactin was isolated from an uncultured Gram-negative β-proteobacterium (E. terrae ssp. carolina) found in sandy soil from North Carolina. Additionally, they reported the unusual structure and mode of action of clovibactin. Study: An antibiotic from an uncultured bacterium binds to an immutable […]

24

Jul , 2023
Arming phages with heterologous effectors paves the way for successful UTI treatment
Tag: Cell Wall

Arming phages with heterologous effectors paves the way for successful UTI treatment

Recently, bacteriocins, synthetic antimicrobial peptides produced by bacteriophages (phages), are being developed as precision antimicrobials. This antimicrobial agent targets specific cell wall hydrolases, such as phage-derived endolysins, for their particular function. A recent Nature Communications study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes. Therefore, an […]

14

Jul , 2023
Researcher receives $2.7 million grant to study lingering Lyme disease symptoms
Tag: Cell Wall

Researcher receives $2.7 million grant to study lingering Lyme disease symptoms

An estimated 1,200 Americans, on average, are diagnosed with Lyme disease each day. Some of those patients continue to experience negative effects, even after treatment. Lyme disease researcher Brandon Jutras, associate professor in the College of Agriculture and Life Sciences and affiliated faculty of the Fralin Life Sciences Institute, recently received a $2.7 million grant […]