Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

9

May , 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

In a recent research paper uploaded to the bioRxiv preprint* server, researchers developed and tested novel bispecific antibodies (bsAbs) comprising both the N-terminal domain (NTD) and the receptor binding domain (RBD) for their efficacy against emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs). These antibodies were synthesized using monoclonal antibodies (mAbs) […]

4

Sep , 2023

Tag: ACE2

Study characterizes SARS-CoV-2 subvariants to inform development of next-generation COVID-19 vaccines

In a recent preprint posted to the bioRxiv* server, researchers characterized two novel XBB variants, EG.5.1 and XBB.2.3, with the former on track to become the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant. Study: Immune Evasion and Membrane Fusion of SARS-CoV-2 XBB Subvariants EG.5.1 and XBB.2.3. Image Credit: Kateryna Kon/Shutterstock.com*Important notice: bioRxiv publishes preliminary […]

12

Jul , 2023

Tag: ACE2

How does SARS-CoV-2 affect the placenta during pregnancy?

In a recent study published in Med, researchers examine host responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within the placenta using transcriptomics. Study: SARS-CoV-2 niches in human placenta revealed by spatial transcriptomics. Image Credit: SciePro / Shutterstock.com Background Previous studies have provided limited insights into SARS-CoV-2 replication during pregnancy, despite using placenta single-cell transcriptomes. […]