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8 Excellent Menswear Additions for Summer from Ben Sherman
8 Excellent Menswear Additions for Summer from Ben Sherman
How to Balance Online Dating With Daily Life – Dating Relationship Coaching & Advice
How to Balance Online Dating With Daily Life – Dating Relationship Coaching & Advice
8 of the best men’s slip on shoes this summer
8 of the best men’s slip on shoes this summer
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10

Jul , 2024
Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation
Tag: Transcription

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand. How RNAP […]

12

Jun , 2024
Natural antioxidants could delay age-related decline in male testosterone production
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Natural antioxidants could delay age-related decline in male testosterone production

In a recent review published in the Nutrients, a group of authors reviewed the use of natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males. Study: Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants. Image Credit: marilyn barbone/Shutterstock.com Background  Androgens are primarily produced by Leydig cells in the testes and are […]

26

May , 2024
Study sheds new light on the intricate molecular mechanisms underlying schizophrenia
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Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging. In a new study, published May 23 is Science, a team led by McLean Hospital researchers used comprehensive genetic and cellular analyses […]

8

May , 2024
Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness
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Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

Retinal degeneration can be inherited or acquired. In the former case, it is an incurable and progressive condition. A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss. Study: Gene Editing for CEP290-Associated Retinal Degeneration. Image […]

24

Apr , 2024
Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes
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Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

With millions of cases of bladder cancer (BC) around the world, the need for tools to ensure a timely diagnosis of this condition is a matter of concern. Scientists recently used mitochondrial-related genes (MRGs), known to be involved in the progression of the disease, to build a novel diagnostic model using machine learning (ML). The […]

5

Mar , 2024
New method simplifies production of limb progenitor cells from fibroblasts
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New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or “reprogram” fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells. Publishing in Developmental Cell, the researchers’ findings have enhanced our understanding of limb development and have set […]

19

Jan , 2024
Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2
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Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

In a recent study in Nature Microbiology, researchers compared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) replication in human cell lines and primary airway cultures and measured host responses to infection. Study: Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants. Image Credit: Naeblys/Shutterstock.comBackground SARS-CoV-2 evolution has led to […]

22

Sep , 2023
the future of mRNA vaccine analysis and quality assurance?
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the future of mRNA vaccine analysis and quality assurance?

In a recent study published in Nature Communications, researchers proposed a simplified approach for analyzing messenger ribonucleic acid (mRNA) vaccines using long-read sequencing. Study: mRNA vaccine quality analysis using RNA sequencing. Image Credit: Jo Panuwat D/Shutterstock.comBackground Messenger RNA vaccines demonstrated safety and efficacy during the COVID-19 pandemic, but extensive quality and purity testing is required […]

21

Aug , 2023
Study sheds light on how SARS-CoV-2 virus switches between replication and packaging
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Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell’s metabolic pathways to produce its proteins and make sure that its genetic material (the RNA genome) is copied. The RNA genome is then packaged very compactly into new virus particles that […]

15

Aug , 2023
Is COVID-19 self-testing effective?
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Is COVID-19 self-testing effective?

In a recent study published in medRxiv*, researchers evaluated real-world evidence on the performance of coronavirus disease 2019 (COVID-19) self-testing strategies (COVIDSTs). Study: Self-tests for COVID-19: what is the evidence? A living systematic review and meta-analysis (2020-2023). Image Credit: Basilico Studio Stock/Shutterstock.com*Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be […]

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