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Vegan diets and skin inflammatory disorders: whats the link?

A recent study published in the Journal of Clinical Medicine reviewed skin disorders and inflammatory conditions associated with nutritional deficiencies in vegan diets. Study: Vegan Diet in Dermatology: A Review. Image Credit: RONEDYA/Shutterstock.com Background Excess or inadequate consumption of nutrients might be associated with skin disorders, such as psoriasis, acne vulgaris, atopic dermatitis (AD), and hidradenitis suppurativa […]

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How is next-generation protein sequencing democratizing protein sequencing?

What challenges do researchers usually encounter with conventional proteomic methods? The proteomics field is highly complex, spanning initial biological samples to comprehensive analysis. An overarching theme repeatedly emphasized by researchers revolves around the absence of a universal solution for this entire process. Rather, each phase demands meticulous harmonization. Researchers often find themselves at a crossroads. They must […]

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Scientists discover new role for liver tPA in regulating cholesterol levels

Despite advances in treatment for high cholesterol, heart disease remains the leading cause of death in the U.S. Scientists at the Medical College of Wisconsin (MCW) are investigating the role of a form of cholesterol called very-low-density lipoprotein – and their findings may lead to new treatment options in the future. The research team is […]

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Alzheimer’s screening just got easier, more accurate with new blood test

A new blood test called p-tau217 shows promise as an Alzheimer’s disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology. That is an innovation now presented by researchers at the University of Gothenburg, together with colleagues at University of […]

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Researchers unravel structure of MCM8/9 enzyme linked to infertility and cancer

Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this. For 15 years, Trakselis has been interested in the MCM8/9 enzyme. Part of the minichromosome […]

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Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell’s metabolic pathways to produce its proteins and make sure that its genetic material (the RNA genome) is copied. The RNA genome is then packaged very compactly into new virus particles that […]

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Sulfate groups on complex sugar molecules affect brain plasticity

Can you recognize someone you haven’t seen in years, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to remember familiar faces or learn new skills, but the molecular basis of this process isn’t well understood. Today, scientists report that sulfate groups on complex sugar molecules called glycosaminoglycans (GAGs) affect […]

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Salk scientists find new immunotherapy treatment for glioblastoma

Glioblastoma, the most common and deadly form of brain cancer, grows rapidly to invade and destroy healthy brain tissue. The tumor sends out cancerous tendrils into the brain that make surgical tumor removal extremely difficult or impossible. Now, Salk scientists have found the immunotherapy treatment anti-CTLA-4 leads to considerably greater survival of mice with glioblastoma. […]

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NCI funds study to investigate the underlying cellular mechanisms that drive ER+ breast cancer

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer. Specifically, how malignant cells with different kinds of mutations and genetics in estrogen receptor-positive (ER+) breast cancer are able to […]

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