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Arming phages with heterologous effectors paves the way for successful UTI treatment
Recently, bacteriocins, synthetic antimicrobial peptides produced by bacteriophages (phages), are being developed as precision antimicrobials. This antimicrobial agent targets specific cell wall hydrolases, such as phage-derived endolysins, for their particular function. A recent Nature Communications study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes. Therefore, an […]