Tag: Software
Exploring the effects of N1-methylpseudouridine in mRNA translation
In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal frameshifting and the overall fidelity of mRNA translation. Study: N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting. Image Credit: MattL_Images/Shutterstock.comBackground Therapeutic in vitro-transcribed (IVT) mRNAs, like those in COVID-19 vaccines, often […]