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Ineos Grenadier Quartermaster Kaiju Overlander
Ineos Grenadier Quartermaster Kaiju Overlander
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Bleu de Chanel Review (2024) A Favorite Cologne For Men
Bleu de Chanel Review (2024) A Favorite Cologne For Men
MENS HEALTH FITS. ALL RIGHTS RESERVED.

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Dec , 2023
Exploring the effects of N1-methylpseudouridine in mRNA translation
Tag: Protein

Exploring the effects of N1-methylpseudouridine in mRNA translation

In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal frameshifting and the overall fidelity of mRNA translation. Study: N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting. Image Credit: MattL_Images/Shutterstock.comBackground  Therapeutic in vitro-transcribed (IVT) mRNAs, like those in COVID-19 vaccines, often […]

26

Nov , 2023
Heat shock protein protects bacteria from plasma treatment
Tag: Protein

Heat shock protein protects bacteria from plasma treatment

A heat shock protein protects the cells against protein clumping. It degrades, however, over longer treatment periods. Plasmas are used, for example, in wound treatment against pathogens that are resistant to antibiotics. However, bacteria can defend themselves: They employ a heat shock protein that protects them. A research team headed by Professor Julia Bandow and […]

25

Nov , 2023
Scientists succeed in mapping a central part of the immune system
Tag: Protein

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system – the HLA class II molecules – while accurately predicting how they display fragments of pathogens on the surface of cells. When we are sick, our immune system – in curing us – relies on […]

24

Nov , 2023
High dietary insulin index associated with increased risk of metabolic unhealthiness, research show
Tag: Protein

High dietary insulin index associated with increased risk of metabolic unhealthiness, research show

A recent Scientific Reports study explored the association between dietary insulin index (DII) and dietary insulin load (DIL) with metabolic healthy (MH) status and the serum levels of brain-derived neurotrophic factor (BDNF) and adropin among the Iranian adult population. Study: Association between dietary insulin index and load with brain derived neurotrophic factor, adropin and metabolic health status […]

18

Nov , 2023
Stem-cell-derived brain cells hold promise for Alzheimer’s, Parkinson’s research
Tag: Protein

Stem-cell-derived brain cells hold promise for Alzheimer’s, Parkinson’s research

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer’s and Parkinson’s diseases and used the discovery to grow the neurons from stem cells for the first time. The stem-cell-derived norepinephrine neurons of the type found […]

15

Nov , 2023
Cannabis shows promise in easing endometriosis pain, new research suggests
Tag: Protein

Cannabis shows promise in easing endometriosis pain, new research suggests

In a recent study published in the Journal of Clinical Medicine, researchers reviewed available literature on cannabis as a self-management strategy in the treatment of pain arising due to endometriosis. They further investigated the mechanisms by which cannabis interacts with the endocannabinoid system (ECS) and the interactions of gut microbiota and ECS in treating the […]

11

Nov , 2023
DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health
Tag: Protein

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Neurodegenerative diseases like Alzheimer’s and Parkinson’s can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE’s Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes. To this end, she aims to examine the function of the […]

4

Nov , 2023
Sparsentan may be a new treatment option for focal segmental glomerulosclerosis
Tag: Protein

Sparsentan may be a new treatment option for focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a rare kidney disorder that affects children and adults, and can lead to kidney failure. New findings from a team led by the University of Minnesota Medical School show patients with FSGS who were treated with the medication sparsentan experienced improved kidney function-; making it a potential new treatment option […]

28

Oct , 2023
Receptor structure-based virtual screening identifies a promising p38α inhibitor
Tag: Protein

Receptor structure-based virtual screening identifies a promising p38α inhibitor

Announcing a new publication for Acta Materia Medica journal. Mitogen-activated protein kinases (MAPKs) are a group of serine-threonine protein kinases that can be activated by extracellular stimuli. MAPK14 (p38α) affects major disease processes, while inhibition of p38α has been shown to have potential therapeutic effects. Many inhibitors targeting p38α have entered clinical trials but have […]

27

Oct , 2023
AI-designed drug candidate shows promise for gastric acid inhibition
Tag: Protein

AI-designed drug candidate shows promise for gastric acid inhibition

Researchers at Nagoya University in Japan created and improved artificial intelligence (AI) designs to synthesize a candidate compound for a new gastric acid inhibitor with a better binding affinity than existing drugs. Their findings, published in Communications Biology, suggest a new way to work in tandem with AI to develop pharmaceuticals. Stomach acid is a […]
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