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Zenith Takes Inspiration from the Jungle with Its Latest Defy Extreme Chronograph
Zenith Takes Inspiration from the Jungle with Its Latest Defy Extreme Chronograph
Russell Moccasin Oneida Review: How This Design Crushed the Modern Slipper
Russell Moccasin Oneida Review: How This Design Crushed the Modern Slipper
Life Lessons of an 81-Year-Old Men’s Mental Health Maverick
Life Lessons of an 81-Year-Old Men’s Mental Health Maverick
MENS HEALTH FITS. ALL RIGHTS RESERVED.

9

Aug , 2024
Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier
Tag: Protein

Novel molecular signaling pathway found to play a crucial role in maintaining the skin barrier

Our skin–the body’s largest organ–provides the first line of defense against infections and many other threats to our health. Decades of research has shown that a wide range of diseases can occur, or become worse, when the skin cannot form an effective barrier. Now, experts in human genetics and asthma research at Cincinnati Children’s report […]

8

Aug , 2024
Review of fasting-mimicking diets in cancer treatment
Tag: Protein

Review of fasting-mimicking diets in cancer treatment

In a recent review published in Cell Metabolism, researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy. Study: Cyclic fasting-mimicking diet in cancer treatment: Preclinical and clinical evidence. Image Credit: vetre/Shutterstock.com FMDs have anticancer properties that potentiate conventional therapies and protect normal tissues. In phase 1/2 clinical studies, cyclic FMD […]

6

Aug , 2024
Addressing Important Cardiac Biology Questions with Proteomics
Tag: Protein

Addressing Important Cardiac Biology Questions with Proteomics

In this interview conducted at Pittcon 2024, we spoke to Professor John Yates from the Scripps Research Institute about capturing cardiomyocyte cell-to-cell heterogeneity via shotgun top-down proteomics. Could you please introduce yourself and briefly describe the main focus of your research and what inspired you to start your work in proteomics?  My name is John […]

31

Jul , 2024
Wildlife species show high SARS-CoV-2 exposure linked to human activity
Tag: Protein

Wildlife species show high SARS-CoV-2 exposure linked to human activity

In a recent study published in the journal Nature Communications, researchers in the United States of America analyzed 23 wildlife species for exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They investigated the effect of human activity and urbanization on seropositivity. They found the presence of SARS-CoV-2 ribonucleic acid (RNA) in six wildlife species […]

28

Jul , 2024
Breakthrough therapy heals spinal cord injuries
Tag: Protein

Breakthrough therapy heals spinal cord injuries

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving “dancing molecules,” to repair tissues and reverse paralysis after severe spinal cord injuries. Now, the same research group has applied the therapeutic strategy to damaged human cartilage cells. In the new study, the treatment activated the gene expression necessary to regenerate cartilage […]

27

Jul , 2024
Scientists explore early life factors contributing to SMA
Tag: Protein

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies […]

25

Jul , 2024
Proof-of-concept animal studies demonstrate a step forward in the fight against HIV
Tag: Protein

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University’s Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature‘s Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications. Scientists have made great strides in the treatment of HIV (human immunodeficiency virus) over the […]

21

Jul , 2024
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
Tag: Protein

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania’s Perelman School of Medicine […]

14

Jul , 2024
Study reveals how inflammation weakens muscles during illness
Tag: Protein

Study reveals how inflammation weakens muscles during illness

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the […]

12

Jul , 2024
CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma
Tag: Protein

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven’t experienced improvement with chemotherapy treatments. But if this CAR-T treatment fails, or the cancer returns yet again -; as happens in approximately half of […]
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