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Hoffman Process Review: Despite Critisism I Paid $6,000 To Share Feelings With 19 Strangers In Byron Bay
Hoffman Process Review: Despite Critisism I Paid $6,000 To Share Feelings With 19 Strangers In Byron Bay
A Traveler’s Guide to Getting It Right
A Traveler’s Guide to Getting It Right
6 of the best men’s flannel shirts from MuskOx
6 of the best men’s flannel shirts from MuskOx
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27

Jul , 2024
Scientists explore early life factors contributing to SMA
Tag: Pathology

Scientists explore early life factors contributing to SMA

Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the Dresden University of Technology are now drawing attention to previously unnoticed abnormalities in embryonic development. They base their argument on studies […]

11

Jul , 2024
Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer
Tag: Pathology

Researchers identify two risk factors that indicate higher risk of aggressive prostate cancer

A recent European Urology Oncology study assessed the mortality risks, based on the Gleason score and clinical parameters, in patients with prostate cancer (PC). Study: Mortality Risk for Patients with Biopsy Gleason Grade Group 1 Prostate Cancer. Image Credit: Korawat photo shoot/Shutterstock.com Prostate cancer and Gleason score The Gleason score is a scoring system that […]

29

May , 2024
Researchers overturn the prevailing theory for colorectal tumor initiation
Tag: Pathology

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear. The results, published on May 29 in Developmental Cell, overturn the prevailing theory for colorectal tumor initiation and suggest new ways to diagnose the disease before it has […]

8

May , 2024
APOE4 gene linked to early onset Alzheimer’s, target for therapeutic intervention
Tag: Pathology

APOE4 gene linked to early onset Alzheimer’s, target for therapeutic intervention

In a recent study published in the journal Nature Medicine, researchers investigated the effect of APOE4 (short for Apolipoprotein E4) homozygosity on Alzheimer’s disease (AD) using pathological, clinical, and biomarker analyses. They found that APOE4 homozygotes showed AD pathology and elevated AD biomarker levels from 55 years of age, representing a distinct variant of AD […]

4

Apr , 2024
Infertile men more likely to have impaired kidney function, study says
Tag: Pathology

Infertile men more likely to have impaired kidney function, study says

In a recent study published in the journal Scientific Reports, researchers investigated the association between male infertility and renal function. They used a large cohort comprising 11,602 participants (5,494 childless men and 6,108 fathers). They found that childless men were likelier to have a low estimated glomerular filtration rate (< 60 ml/min/1.73m2) and dipstick proteinuria independent of […]

3

Apr , 2024
Researchers find a promising approach to remove amyloid plaques in Alzheimer’s disease
Tag: Pathology

Researchers find a promising approach to remove amyloid plaques in Alzheimer’s disease

Alzheimer’s disease starts with a sticky protein called amyloid beta that builds up into plaques in the brain, setting off a chain of events that results in brain atrophy and cognitive decline. The new generation of Alzheimer’s drugs -; the first proven to change the course of the disease -; work by tagging amyloid for […]

29

Feb , 2024
PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases
Tag: Pathology

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University. This partnership will focus on ‘gene-based environmental biomarkers,’ known as epigenetic markers, for calculating risk scores for Alzheimer’s disease. Together with ALZmetrixTM, PharmaKure’s blood-based biomarker, this will increase the […]

7

Jan , 2024
Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy
Tag: Pathology

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment. They also found a way to deliver immunotherapy’s cancer-killing impact without the unwelcome side effect. The findings are published in Science. This is a good example of how understanding a mechanism […]

3

Jan , 2024
Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection
Tag: Pathology

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice. The study, from researchers at Washington University School of Medicine in St. Louis, is published Jan. 3 […]

29

Nov , 2023
Targeting personality traits could be a way to reduce dementia risk
Tag: Pathology

Targeting personality traits could be a way to reduce dementia risk

People with personality traits such as conscientiousness, extraversion and positive affect are less likely to be diagnosed with dementia than those with neuroticism and negative affect, according to a new analysis by researchers at the University of California, Davis and Northwestern University. The difference was not linked to physical damage to brain tissue found in […]
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