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8 of the best men’s shoes for summer from HEYDUDE
8 of the best men’s shoes for summer from HEYDUDE
The Billionaire Clobber Revolution – Why the Men Are Boring and the Riviera Is Blooming
The Billionaire Clobber Revolution – Why the Men Are Boring and the Riviera Is Blooming
The Compassionate Warrior: The Power of Mature Masculine Psychology
The Compassionate Warrior: The Power of Mature Masculine Psychology
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21

Jul , 2024
CD5 knockout using CRISPR boosts CAR T cell therapy efficacy
Tag: Pancreatic Cancer

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania’s Perelman School of Medicine […]

10

Jul , 2024
Blocking nidogen-2 enhances chemotherapy efficacy in pancreatic cancer
Tag: Pancreatic Cancer

Blocking nidogen-2 enhances chemotherapy efficacy in pancreatic cancer

Researchers at the Garvan Institute of Medical Research have identified a potential new therapeutic target for pancreatic cancer, one of the most lethal cancer types with limited treatment options. Published in the journal Science Advances, the study shows that blocking the molecule nidogen-2 enhanced the effectiveness of chemotherapy and reduced the cancer’s spread in mouse […]

27

Jun , 2024
Fighting cancer with nanoparticles
Tag: Pancreatic Cancer

Fighting cancer with nanoparticles

According to the European Commission, cancer is on the rise in the EU, with the number of new cases reaching 2.7 million in 2022. Cancer deaths for that same year also went up and were estimated to be at 1.3 million. In particular, pancreatic cancer remained the leading cause of cancer-related deaths in the EU […]

24

Jun , 2024
Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer
Tag: Pancreatic Cancer

Researchers win $2.78 million grant to harness AI for precision treatment in rectal cancer

With a new five-year, $2.78 million grant from the National Institutes of Health and National Cancer Institute, researchers at Case Western Reserve University(CWRU), Cleveland Clinic and University Hospitals (UH) will use artificial intelligence (AI) to better treat rectal cancer patients. The American Cancer Society estimates about 46,000 people nationally will be diagnosed this year with rectal cancer-;the […]

6

Apr , 2024
UCLA study finds pre-surgery immunotherapy safe for pancreatic cancer patients
Tag: Pancreatic Cancer

UCLA study finds pre-surgery immunotherapy safe for pancreatic cancer patients

Findings A pilot study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy before surgery is safe and may improve long-term outcomes. The findings showed that treating patients with the combination therapy prior to surgery resulted in a higher rate of successful […]

26

Mar , 2024
Study unveils link between oral bacteria and pancreatic cancer development in mice
Tag: Pancreatic Cancer

Study unveils link between oral bacteria and pancreatic cancer development in mice

New study unveils a significant connection between oral bacteria and pancreatic cancer development in mice and sheds light on a previously recognized link between oral health and pancreatic cancer, one of the deadliest forms of cancer. Prof. Gabriel Nussbaum and his team at the Institute of Biomedical and Oral Research, Hebrew University-Hadassah Faculty of Dental […]

4

Feb , 2024
New vaccine may be potential off-the-shelf treatment for pancreatic, colorectal cancer
Tag: Pancreatic Cancer

New vaccine may be potential off-the-shelf treatment for pancreatic, colorectal cancer

A new vaccine shows encouraging early results as a potential off-the-shelf treatment for certain patients with pancreatic or colorectal cancer, according to a study co-led by researchers at Memorial Sloan Kettering Cancer Center (MSK). The vaccine targets tumors with mutations (or changes) in the KRAS gene, a driving force in many cancers. This cancer vaccine is different from another type […]

27

Dec , 2023
New drug screening system helps uncover promising target for pancreatic cancer treatments
Tag: Pancreatic Cancer

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine. In the study, published Dec. 26 in Cell Stem Cell, the scientists tested more than 6,000 compounds on their pancreatic tumor […]

6

Dec , 2023
HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors
Tag: Pancreatic Cancer

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar tissue, that surrounds most pancreatic tumors and makes it hard for drugs to access and destroy the cancer cells. Now, […]

6

Aug , 2023
Study helps understand how RNA modification promotes pancreatic cancer
Tag: Pancreatic Cancer

Study helps understand how RNA modification promotes pancreatic cancer

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression. However, while studies into m6A modification of messenger RNA (mRNA) have been extensive, exploration of its impact on lncRNAs, especially within the context of PDAC, has been relatively limited. In an innovative study published […]

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