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Certain gut microbes may be linked to skeletal health

There is growing evidence that a relative abundance of certain gut microbes may be related to skeletal health, according to a new study published in Frontiers in Endocrinology. If confirmed by additional research, the findings could provide the opportunity to alter gut microbiomes to achieve better bone health, as scientists learn more about “osteomicrobiology,” a […]

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Neighborhood disadvantage associated with differences in microstructure of the brain’s cortex

You are what you eat, according to the adage. But it’s not just the body that’s impacted. According to research from UCLA David Geffen School of Medicine, living in a disadvantaged neighborhood can affect food choices, weight gain and even the microstructure of the brain. The study, appearing in Communications Medicine, a Nature journal, finds […]

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Is there an association between waist-calf circumference ratio and all-cause and cause-specific mortality?

In a community-based cohort study published in BMC Public Health, researchers studied how anthropometric measures like the waist-calf circumference ratio (WCR), waist circumference (WC), calf circumference (CC), and body mass index (BMI) are associated with cause-specific and all-cause mortality in elderly adults. They found that a lower CC and higher WCR are associated with an […]

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Postnatal research offers clues to tackling maternal obesity

A study has been conducted at Newcastle University, United Kingdom (UK), to assess postnatal dietary patterns, physical activity status, and changes in body weight among obese women living in a highly deprived region in the UK. The study is published in the Nutrients Journal. Study: Maternal Obesity and Patterns in Postnatal Diet, Physical Activity and Weight […]

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A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals. Abrogation of the NSL genes leads to the death of the organism, and this phenotype gives rise to this complex’s curious name. Max Planck researchers have now identified […]

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Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population. It is characterized by the accumulation of fat in the liver. It is often associated with other conditions, such as obesity, type 2 diabetes, and metabolic syndrome. The new definition of metabolic dysfunction-associated fatty liver […]

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Glucokinase activators induce hepatic lipid accumulation in mice with high-fat diet

The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway. Thus, this study provides clinical reference and theoretical basis for the application of glucokinase activator (GKA) in treating patients with type […]

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Americans want weight loss drugs despite high cost

Many Americans really want to lose weight — and a new poll shows nearly half of adults would be interested in taking a prescription drug to help them do so. At the same time, enthusiasm dims sharply if the treatment comes as an injection, if it is not covered by insurance, or if the weight […]

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Jul , 2023

New weight loss drugs carry high price tags and lots of questions for seniors

Corlee Morris has dieted throughout her adult life. After her weight began climbing in high school, she spent years losing 50 or 100 pounds then gaining it back. Morris, 78, was at her heaviest in her mid-40s, standing 5 feet 10½ inches and weighing 310 pounds. The Pittsburgh resident has had diabetes for more than […]

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Jul , 2023