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6 Best Silk Shirts for Men: Ease into Summer Suavely in 2025
6 Best Silk Shirts for Men: Ease into Summer Suavely in 2025
Terry Cool: The &SONS Maywood Shirt in Seagrass Green
Terry Cool: The &SONS Maywood Shirt in Seagrass Green
Collars and Co Review: Can Dress Shirts Really Meet Polo Comfort?
Collars and Co Review: Can Dress Shirts Really Meet Polo Comfort?
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6

Aug , 2024
Addressing Important Cardiac Biology Questions with Proteomics
Tag: Mutation

Addressing Important Cardiac Biology Questions with Proteomics

In this interview conducted at Pittcon 2024, we spoke to Professor John Yates from the Scripps Research Institute about capturing cardiomyocyte cell-to-cell heterogeneity via shotgun top-down proteomics. Could you please introduce yourself and briefly describe the main focus of your research and what inspired you to start your work in proteomics?  My name is John […]

31

Jul , 2024
Wildlife species show high SARS-CoV-2 exposure linked to human activity
Tag: Mutation

Wildlife species show high SARS-CoV-2 exposure linked to human activity

In a recent study published in the journal Nature Communications, researchers in the United States of America analyzed 23 wildlife species for exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They investigated the effect of human activity and urbanization on seropositivity. They found the presence of SARS-CoV-2 ribonucleic acid (RNA) in six wildlife species […]

25

Jun , 2024
Novel genetic predisposition to being overweight or obese identified
Tag: Mutation

Novel genetic predisposition to being overweight or obese identified

In a recent study published in Med, researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function (LoF) genetic variation in small integral membrane protein 1 (SMIM1) and the general population. Study: SMIM1 absence is associated with reduced energy expenditure and excess weight. Image Credit: james benjamin/Shutterstock.com Background Obesity is […]

8

Jun , 2024
New therapeutic target discovered for treatment-resistant melanoma
Tag: Mutation

New therapeutic target discovered for treatment-resistant melanoma

An international research team led by scientists from the University of Liège (Belgium) has discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies. Inhibition of the VARS enzyme could prevent this therapeutic resistance by resensitizing tumors resistant to these targeted therapies. Melanoma is one of the most serious and […]

4

Jun , 2024
Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC
Tag: Mutation

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognostic markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating […]

11

May , 2024
Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy
Tag: Mutation

Expanding treatment horizons for hypermutated urothelial carcinomas beyond immunotherapy

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, “Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy.” In this new editorial, researcher Ioannis A. Voutsadakis from Sault Area Hospital and Northern Ontario School of Medicine discusses tumor mutation burden (TMB)-;a novel clinical biomarker for prediction of checkpoint inhibitor immunotherapy […]

26

Mar , 2024
Study unveils link between oral bacteria and pancreatic cancer development in mice
Tag: Mutation

Study unveils link between oral bacteria and pancreatic cancer development in mice

New study unveils a significant connection between oral bacteria and pancreatic cancer development in mice and sheds light on a previously recognized link between oral health and pancreatic cancer, one of the deadliest forms of cancer. Prof. Gabriel Nussbaum and his team at the Institute of Biomedical and Oral Research, Hebrew University-Hadassah Faculty of Dental […]

27

Dec , 2023
New drug screening system helps uncover promising target for pancreatic cancer treatments
Tag: Mutation

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine. In the study, published Dec. 26 in Cell Stem Cell, the scientists tested more than 6,000 compounds on their pancreatic tumor […]

5

Nov , 2023
Using ripretinib and surgery to manage recurrent gastrointestinal stromal tumor
Tag: Mutation

Using ripretinib and surgery to manage recurrent gastrointestinal stromal tumor

A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, “Multi-disciplinary management of recurrent gastrointestinal stromal tumor harboring KIT exon 11 mutation with the switch-control kinase inhibitor ripretinib and surgery.” Ripretinib is a tyrosine kinase inhibitor that was approved by the United States FDA in 2020 for treatment of advanced […]

18

Oct , 2023
New treatment options offer hope for patients with non-small cell lung cancer
Tag: Mutation

New treatment options offer hope for patients with non-small cell lung cancer

More people with non-small cell lung cancer (NSCLC) are likely to benefit from new drugs that target molecular alterations in tumor cells, with less need for chemotherapy, following results of multiple landmark clinical trials reported for the first time in late-breaking presentations at the ESMO Congress 2023. Better outcomes were achieved with combinations of experimental […]
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