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Ineos Grenadier Quartermaster Kaiju Overlander
Ineos Grenadier Quartermaster Kaiju Overlander
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Bleu de Chanel Review (2024) A Favorite Cologne For Men
Bleu de Chanel Review (2024) A Favorite Cologne For Men
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Aug , 2023
RARα receptor plays unexpected role in T cell activation
Tag: Molecule

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, but it also now appears to operate outside the […]

24

Jul , 2023
Arming phages with heterologous effectors paves the way for successful UTI treatment
Tag: Molecule

Arming phages with heterologous effectors paves the way for successful UTI treatment

Recently, bacteriocins, synthetic antimicrobial peptides produced by bacteriophages (phages), are being developed as precision antimicrobials. This antimicrobial agent targets specific cell wall hydrolases, such as phage-derived endolysins, for their particular function. A recent Nature Communications study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes. Therefore, an […]

22

Jul , 2023
Researchers uncover novel targets for treatment of schistosomiasis
Tag: Molecule

Researchers uncover novel targets for treatment of schistosomiasis

The worms that cause schistosomiasis (Schistosoma mansoni) are unusual in several ways, especially the fact that male and female adults must stay paired together throughout their lives for reproduction to be successful. Females may produce as many as 3,000 eggs per day. Approximately half reach the host’s gut or bladder. The rest are swept away […]

21

Jul , 2023
ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia
Tag: Molecule

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

ARMGO Pharma, Inc. (ARMGO), a clinical stage biopharmaceutical company advancing a novel class of small molecule drugs known as Rycals®, announced today the enrollment of the first patient in a Phase 2 proof of concept clinical trial using its Rycal ARM210 (also known as S48168), for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). The […]
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