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Ineos Grenadier Quartermaster Kaiju Overlander
Ineos Grenadier Quartermaster Kaiju Overlander
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Jim Green Boots Review: The Armored Trail Runner Taking on Poachers
Bleu de Chanel Review (2024) A Favorite Cologne For Men
Bleu de Chanel Review (2024) A Favorite Cologne For Men
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Mar , 2024
New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread
Tag: Molecule

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique […]

16

Feb , 2024
Aventa Genomics and the Future of Genomic Testing
Tag: Molecule

Aventa Genomics and the Future of Genomic Testing

In this interview, Chris Roberts of Aventa Genomics highlights the groundbreaking Aventa FusionPlus test, detailing its superior ability to detect gene fusions in cancer diagnostics and its pivotal role in advancing personalized oncology treatments. Could you give us a brief overview of Aventa Genomics, including its founding vision and primary mission in the field of […]

4

Feb , 2024
Small-molecule A485 mobilizes white blood cells on demand
Tag: Molecule

Small-molecule A485 mobilizes white blood cells on demand

White blood cells, or leukocytes, are the body’s first and second lines of defense against foreign organisms and particles. However, few drugs target these cells’ production and movement for clinically useful purposes. A new study published in the journal Immunity explores the signaling molecule landscape to identify potentially druggable targets for leukocyte migration into the […]

3

Feb , 2024
CAR T cells target senescent cells, improve healthspan in mice
Tag: Molecule

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the “living drugs” can be harnessed against other diseases, like autoimmune disorders. Now laboratory research led by Memorial Sloan Kettering Cancer Center (MSK) and Cold Spring Harbor Laboratory suggests these engineered immune cells hold promise for treating some diseases […]

3

Jan , 2024
Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection
Tag: Molecule

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice. The study, from researchers at Washington University School of Medicine in St. Louis, is published Jan. 3 […]

10

Dec , 2023
MD Anderson and Rigel partner to expand olutasidenib evaluation in AML and other cancers
Tag: Molecule

MD Anderson and Rigel partner to expand olutasidenib evaluation in AML and other cancers

The University of Texas MD Anderson Cancer Center and Rigel Pharmaceuticals, Inc. today announced a multi-year strategic development collaboration to expand the evaluation of olutasidenib in acute myeloid leukemia (AML) and other hematologic cancers. The alliance brings together MD Anderson’s clinical research expertise with Rigel’s differentiated targeted molecule. Under the strategic collaboration, Rigel and MD […]

25

Nov , 2023
Scientists succeed in mapping a central part of the immune system
Tag: Molecule

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system – the HLA class II molecules – while accurately predicting how they display fragments of pathogens on the surface of cells. When we are sick, our immune system – in curing us – relies on […]

18

Nov , 2023
Machine learning uncovers potent immunomodulators for vaccines and immunotherapy
Tag: Molecule

Machine learning uncovers potent immunomodulators for vaccines and immunotherapy

Small molecules called immunomodulators can help create more effective vaccines and stronger immunotherapies to treat cancer. But finding the molecules that instigate the right immune response is difficult -;the number of drug-like small molecules has been estimated to be 1060, much higher than the number of stars in the visible universe. In a potential first […]

10

Nov , 2023
Andrew Buchanan’s Impact on Biologics Innovation
Tag: Molecule

Andrew Buchanan’s Impact on Biologics Innovation

Following ELRIGs Drug Discovery Conference, News Medical took part in an insightful discussion with Dr. Andrew Buchanan, a renowned figure in the realm of biopharmaceutical research. Dr. Buchanan’s career spans 22 years, notably at Cambridge Antibody Technology, MedImmune, and AstraZeneca, where he has significantly contributed to the development of 18 antibody-based drugs, including three successful […]

5

Sep , 2023
How is next-generation protein sequencing democratizing protein sequencing?
Tag: Molecule

How is next-generation protein sequencing democratizing protein sequencing?

What challenges do researchers usually encounter with conventional proteomic methods? The proteomics field is highly complex, spanning initial biological samples to comprehensive analysis. An overarching theme repeatedly emphasized by researchers revolves around the absence of a universal solution for this entire process. Rather, each phase demands meticulous harmonization. Researchers often find themselves at a crossroads. They must […]
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