Study reveals how inflammation weakens muscles during illness

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Jul , 2024

Study reveals how inflammation weakens muscles during illness

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the […]

12

Jun , 2024

Tag: Mitochondria

Natural antioxidants could delay age-related decline in male testosterone production

In a recent review published in the Nutrients, a group of authors reviewed the use of natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males. Study: Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants. Image Credit: marilyn barbone/Shutterstock.com Background Androgens are primarily produced by Leydig cells in the testes and are […]

30

Apr , 2024

Tag: Mitochondria

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells’ powerhouses, the mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse diet-induced obesity, fatty liver and diabetes in mice. Mitochondria are essential for human […]

24

Apr , 2024

Tag: Mitochondria

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

With millions of cases of bladder cancer (BC) around the world, the need for tools to ensure a timely diagnosis of this condition is a matter of concern. Scientists recently used mitochondrial-related genes (MRGs), known to be involved in the progression of the disease, to build a novel diagnostic model using machine learning (ML). The […]

14

Apr , 2024

Tag: Mitochondria

Researchers unveil a novel strategy for identifying key proteins in organelle communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts. In cellular biology, unraveling the complexities of cellular function at the molecular […]

12

Apr , 2024

Tag: Mitochondria

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures – such as the nucleus, mitochondria or peroxisomes – known as “organelles”. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction. Scientists at the University of Geneva (UNIGE) have combined high-resolution microscopy and kinematic reconstruction techniques to visualize, in […]

15

Dec , 2023

Tag: Mitochondria

Researchers reveal a connection between cellular metabolism and depression, suicidal ideation

Major depressive disorder affects 16.1 million adults in the United States and costs $210 billion annually. While the primary symptoms of depression are psychological, scientists and doctors have come to understand that depression is a complex disease with physical effects throughout the body. For example, measuring markers of cellular metabolism has become an important approach […]

15

Sep , 2023

Tag: Mitochondria

Study upends common belief in what triggers Parkinson’s disease

A new Northwestern Medicine study challenges a common belief in what triggers Parkinson’s disease. Degeneration of dopaminergic neurons is widely accepted as the first event that leads to Parkinson’s. But the new study suggests that a dysfunction in the neuron’s synapses -; the tiny gap across which a neuron can send an impulse to another […]

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