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5 Best Shoe Trees – Cedar and Wooden Options in 2025
5 Best Shoe Trees – Cedar and Wooden Options in 2025
8 of the best men’s casual shirts from Charles Tyrwhitt – ideal for keeping things classy this summer
8 of the best men’s casual shirts from Charles Tyrwhitt – ideal for keeping things classy this summer
6 Best Silk Shirts for Men: Ease into Summer Suavely in 2025
6 Best Silk Shirts for Men: Ease into Summer Suavely in 2025
MENS HEALTH FITS. ALL RIGHTS RESERVED.

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Dec , 2023
HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors
Tag: Genes

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar tissue, that surrounds most pancreatic tumors and makes it hard for drugs to access and destroy the cancer cells. Now, […]

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Nov , 2023
Scientists succeed in mapping a central part of the immune system
Tag: Genes

Scientists succeed in mapping a central part of the immune system

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system – the HLA class II molecules – while accurately predicting how they display fragments of pathogens on the surface of cells. When we are sick, our immune system – in curing us – relies on […]

3

Nov , 2023
Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9
Tag: Genes

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more. In research published in Nature Catalysis, scientists at Florida State University produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 enzyme while it cut strands of DNA, providing clear evidence that magnesium plays a […]

2

Nov , 2023
A Discussion with Dr. Wenning Qin
Tag: Genes

A Discussion with Dr. Wenning Qin

In this interview, we delve deep into the pioneering world of xenotransplantation and the evolving landscape of gene editing, with Dr. Wenning Qin, SVP, Innovation & Process Development at eGenesis. Drawing from her vast experience, Dr. Qin shares insights into the challenges, opportunities, and future of xenotransplantation. Please introduce yourself and tell us about your […]

15

Sep , 2023
Study upends common belief in what triggers Parkinson’s disease
Tag: Genes

Study upends common belief in what triggers Parkinson’s disease

A new Northwestern Medicine study challenges a common belief in what triggers Parkinson’s disease. Degeneration of dopaminergic neurons is widely accepted as the first event that leads to Parkinson’s. But the new study suggests that a dysfunction in the neuron’s synapses -; the tiny gap across which a neuron can send an impulse to another […]

28

Aug , 2023
A new understanding of the role of the NSL complex
Tag: Genes

A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals. Abrogation of the NSL genes leads to the death of the organism, and this phenotype gives rise to this complex’s curious name. Max Planck researchers have now identified […]

19

Aug , 2023
RARα receptor plays unexpected role in T cell activation
Tag: Genes

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, but it also now appears to operate outside the […]

6

Aug , 2023
Study helps understand how RNA modification promotes pancreatic cancer
Tag: Genes

Study helps understand how RNA modification promotes pancreatic cancer

Chemical modifications of RNA molecules, such as m6A, can critically impact gene expression, influencing various aspects of cancer development and progression. However, while studies into m6A modification of messenger RNA (mRNA) have been extensive, exploration of its impact on lncRNAs, especially within the context of PDAC, has been relatively limited. In an innovative study published […]

4

Aug , 2023
New study provides promising results for metformin in periodontitis
Tag: Genes

New study provides promising results for metformin in periodontitis

Periodontitis, a prevalent global health concern, results in the gradual destruction of tooth-supporting tissues and is often exacerbated by oxidative stress conditions and bacterial changes. Current treatment methodologies include mechanical debridement, anti-inflammatory drugs, and regenerative surgery. The researchpublished in the journal of Genes & Diseases, conducted detailed examinations on cellular interactions with Metformin, investigating its […]

24

Jul , 2023
Arming phages with heterologous effectors paves the way for successful UTI treatment
Tag: Genes

Arming phages with heterologous effectors paves the way for successful UTI treatment

Recently, bacteriocins, synthetic antimicrobial peptides produced by bacteriophages (phages), are being developed as precision antimicrobials. This antimicrobial agent targets specific cell wall hydrolases, such as phage-derived endolysins, for their particular function. A recent Nature Communications study demonstrated how phage can be engineered to produce bacteriocins and cell wall hydrolases as antimicrobial effector genes. Therefore, an […]
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