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LANX Ribchester Boots: Your New Go-To for Tackling the Great Outdoors in Style
LANX Ribchester Boots: Your New Go-To for Tackling the Great Outdoors in Style
Arne’s Big Move: From Digital Darling to Real-World Power Player
Arne’s Big Move: From Digital Darling to Real-World Power Player
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
Storm-Ready Style: The Finisterre Longline Stormbird Waterproof Jacket is a Coastal Crusader
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24

May , 2024
Researchers produce advanced multidimensional maps of gene regulation networks in the brain
Tag: Genes

Researchers produce advanced multidimensional maps of gene regulation networks in the brain

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain’s biological pathways and cellular functions. The research, supported the National Institutes of Health (NIH), used postmortem brain […]

22

May , 2024
Ancient viral sequences in the human genome may contribute to psychiatric disorder susceptibility
Tag: Genes

Ancient viral sequences in the human genome may contribute to psychiatric disorder susceptibility

New research led by King’s College London has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to susceptibility for psychiatric disorders such as schizophrenia, bipolar disorder, and depression. Published in Nature Communications, the study was part-funded by the National Institute for Health and Care […]

8

May , 2024
Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness
Tag: Genes

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

Retinal degeneration can be inherited or acquired. In the former case, it is an incurable and progressive condition. A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss. Study: Gene Editing for CEP290-Associated Retinal Degeneration. Image […]

8

May , 2024
APOE4 gene linked to early onset Alzheimer’s, target for therapeutic intervention
Tag: Genes

APOE4 gene linked to early onset Alzheimer’s, target for therapeutic intervention

In a recent study published in the journal Nature Medicine, researchers investigated the effect of APOE4 (short for Apolipoprotein E4) homozygosity on Alzheimer’s disease (AD) using pathological, clinical, and biomarker analyses. They found that APOE4 homozygotes showed AD pathology and elevated AD biomarker levels from 55 years of age, representing a distinct variant of AD […]

24

Apr , 2024
Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes
Tag: Genes

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

With millions of cases of bladder cancer (BC) around the world, the need for tools to ensure a timely diagnosis of this condition is a matter of concern. Scientists recently used mitochondrial-related genes (MRGs), known to be involved in the progression of the disease, to build a novel diagnostic model using machine learning (ML). The […]

18

Apr , 2024
Study pinpoints 95 locations in the genome associated with risk of developing PTSD
Tag: Genes

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person’s quality of life. About 6 percent of people who experience trauma develop the disorder, but scientists don’t yet understand the neurobiology underlying PTSD.  Now, a new genetic study of more than 1.2 million […]

5

Mar , 2024
New method simplifies production of limb progenitor cells from fibroblasts
Tag: Genes

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or “reprogram” fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells. Publishing in Developmental Cell, the researchers’ findings have enhanced our understanding of limb development and have set […]

3

Mar , 2024
Exploring the epigenetic impact of smoking across racial and ethnic groups
Tag: Genes

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses. But the link between epigenetics (the study of mechanisms that impact gene expression) and smoking is not fully understood, especially in terms of differences across racial and ethnic groups. We know that smoking affects […]

29

Feb , 2024
PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases
Tag: Genes

PharmaKure announces epigenetics collaboration with Sheffield Hallam University to understand mechanisms of Alzheimer’s Diseases

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University. This partnership will focus on ‘gene-based environmental biomarkers,’ known as epigenetic markers, for calculating risk scores for Alzheimer’s disease. Together with ALZmetrixTM, PharmaKure’s blood-based biomarker, this will increase the […]

21

Feb , 2024
Physical inactivity and inflammation drive age-related gene changes in skeletal muscles
Tag: Genes

Physical inactivity and inflammation drive age-related gene changes in skeletal muscles

New research indicates that some age-related changes in gene and protein expression in the skeletal muscles of older individuals may be affected more by physical inactivity and chronic inflammation than primary aging, or intrinsic maturational processes. Physical inactivity and chronic inflammation are the most important drivers of secondary aging, or changes over time that are […]
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