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This PT’s Squat Tip Is “Game-Changing”—And It’s Surprisingly Simple
This PT’s Squat Tip Is “Game-Changing”—And It’s Surprisingly Simple
The Best Beginner Exercises, As Picked By Five Personal Trainers
The Best Beginner Exercises, As Picked By Five Personal Trainers
8 Best Dress Shirts for Big Guys – Big & Tall Picks For 2025
8 Best Dress Shirts for Big Guys – Big & Tall Picks For 2025
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Mar , 2024
Rapid, easy-to-use diagnostic test could save more lives from melioidosis
Tag: Efficacy

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed. A new rapid test could save lives by diagnosing patients in hours, rather than several days taken by current bacterial culture methods, meaning they receive the correct antibiotics faster. The test uses CRISPR to detect […]

7

Mar , 2024
COVID-19 booster enhances virus neutralizing antibodies in breast milk, new study reveals
Tag: Efficacy

COVID-19 booster enhances virus neutralizing antibodies in breast milk, new study reveals

In a recent study published in Frontiers, researchers investigated the transmission- and immunoglobulin G (IgG) viral neutralization potential of coronavirus disease 2019 (COVID-19) booster vaccine products (antibodies) passed from mother to offspring through breastmilk. They evaluated the IgG concentrations of milk, plasma, and stool samples from 24 infants and 34 vaccinated mothers, 14 of whom […]

2

Mar , 2024
Microbial signatures linked to immunotherapy response across cancers
Tag: Efficacy

Microbial signatures linked to immunotherapy response across cancers

The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma. Researchers from the Wellcome Sanger Institute, the Olivia Newton-John Cancer Research Institute in Australia, and collaborators, have identified specific strains of bacteria that are linked with a positive response to combination immunotherapy […]

14

Feb , 2024
Hormonal steroids found to boost drug resistance in gonorrhea bacteria
Tag: Efficacy

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

In a recent study published in Nature Communications, researchers performed cellular, biochemical, and structural analyses to assess the multiple transferable resistance repressor (MtrR) binding and activation by male and female steroidal hormones, physiologically significant molecules interacting with gonococcal organisms during infection. Neisseria gonorrhoeae is a gram-negative diplococcus that causes millions of diseases globally, including those […]

12

Feb , 2024
Drug repurposing study finds lonafarnib effective against RSV
Tag: Efficacy

Drug repurposing study finds lonafarnib effective against RSV

In a study published in the journal Nature Communications, researchers screened ReFRAME (short for repurposing, focused rescue, and accelerated Medchem), a drug-repurposing library, for drugs against respiratory syncytial virus (RSV). They identified lonafarnib as a potent inhibitor of RSV fusion protein and investigated its therapeutic potential against an RSV infection. Study: Drug repurposing screen identifies […]

3

Feb , 2024
CAR T cells target senescent cells, improve healthspan in mice
Tag: Efficacy

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the “living drugs” can be harnessed against other diseases, like autoimmune disorders. Now laboratory research led by Memorial Sloan Kettering Cancer Center (MSK) and Cold Spring Harbor Laboratory suggests these engineered immune cells hold promise for treating some diseases […]

19

Jan , 2024
Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2
Tag: Efficacy

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

In a recent study in Nature Microbiology, researchers compared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) replication in human cell lines and primary airway cultures and measured host responses to infection. Study: Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants. Image Credit: Naeblys/Shutterstock.comBackground SARS-CoV-2 evolution has led to […]

17

Jan , 2024
Which wins for heart failure patients with depression?
Tag: Efficacy

Which wins for heart failure patients with depression?

In a recent article published in JAMA Network Open, researchers compared the efficacy of antidepressant medication management (MEDS) against behavioral activation psychotherapy (BA) among inpatients admitted to a hospital with heart failure (HF) and outpatients presenting to clinics for HF follow-up, both experiencing depressive symptoms. They conducted a randomized controlled trial (RCT) between 2018 and 2022, […]

16

Jan , 2024
Nanobots for bladder cancer treatment, promising high efficacy and targeted delivery
Tag: Efficacy

Nanobots for bladder cancer treatment, promising high efficacy and targeted delivery

Bladder cancer is currently treated in its earlier stages by localized intravesical chemotherapy or immunotherapy after removing the tumor. However, recurrences occur in up to 70% of patients at 5 years, while up to 30% fail to respond. This means a constant need to monitor and retreat these patients, driving costs sky-high for the treatment […]

15

Jan , 2024
Universal Coronavirus vaccine could save billions in U.S., new study suggests
Tag: Efficacy

Universal Coronavirus vaccine could save billions in U.S., new study suggests

In a recent study published in eClinicalMedicine, researchers evaluated the epidemiologic, clinical, and economic value of a universal coronavirus disease 2019 (COVID-19) vaccine under varying circumstances, such as the advent of a new coronavirus, using a computational simulation model. Study: The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study. Image […]
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