Tag: Down Syndrome
APOE4 gene linked to early onset Alzheimer’s, target for therapeutic intervention
In a recent study published in the journal Nature Medicine, researchers investigated the effect of APOE4 (short for Apolipoprotein E4) homozygosity on Alzheimer’s disease (AD) using pathological, clinical, and biomarker analyses. They found that APOE4 homozygotes showed AD pathology and elevated AD biomarker levels from 55 years of age, representing a distinct variant of AD […]