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It’s Time Australian Men Have An Honest Conversation About Being Better
It’s Time Australian Men Have An Honest Conversation About Being Better
5 Best Shoe Trees – Cedar and Wooden Options in 2025
5 Best Shoe Trees – Cedar and Wooden Options in 2025
8 of the best men’s casual shirts from Charles Tyrwhitt – ideal for keeping things classy this summer
8 of the best men’s casual shirts from Charles Tyrwhitt – ideal for keeping things classy this summer
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22

Nov , 2023
Enabling PacBio customers to optimize size selection for long-read sequencing libraries
Tag: DNA

Enabling PacBio customers to optimize size selection for long-read sequencing libraries

Yourgene Health (part of the Novacyt group of companies), a leading international molecular diagnostics group, and PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced a collaboration to optimize size selection for long-read sequencing workflows. PacBio has qualified Yourgene’s LightBench® instrument for size selection of long DNA fragments, enabling high yields for […]

9

Nov , 2023
Study unveils complex admixture in European ancestry populations
Tag: DNA

Study unveils complex admixture in European ancestry populations

A recent study published in the journal Nature Communications provides evidence of subcontinental admixture in people with European ancestry, in contrast to previous genetic association studies that recognize European ancestry populations as stratified and not as admixed.   Study: Unappreciated subcontinental admixture in Europeans and European Americans and implications for genetic epidemiology studies. Image Credit: Pixels Hunter […]

3

Nov , 2023
Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9
Tag: DNA

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more. In research published in Nature Catalysis, scientists at Florida State University produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 enzyme while it cut strands of DNA, providing clear evidence that magnesium plays a […]

10

Oct , 2023
Breast milk microbiome changes after COVID-19 vaccination, linked to enhanced infant protection
Tag: DNA

Breast milk microbiome changes after COVID-19 vaccination, linked to enhanced infant protection

In a recent study published in the journal npj Vaccines, researchers investigated whether the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger ribonucleic acid (mRNA) vaccine could alter the breast milk microbiome and ways in which the changes impact breast milk antibody titers. Vaccine-induced antibodies in breast milk confer immunity to newborns against SARS-CoV-2. However, […]

27

Sep , 2023
Could baseline gut microbiota and metabolome help predict the durability of immune responses elicited by different COVID-19 vaccines?
Tag: DNA

Could baseline gut microbiota and metabolome help predict the durability of immune responses elicited by different COVID-19 vaccines?

In a prospective longitudinal study published in the Journal of Signal Transduction and Targeted Therapy, researchers characterized the gut microbiota composition associated with the durability of coronavirus disease 2019 (COVID-19) vaccine-induced immunity. Additionally, they determined the impact of COVID-19 vaccines on long-term gut microbiota changes. To this end, they created two groups comprising people vaccinated with CoronaVac […]

22

Sep , 2023
Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials
Tag: DNA

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient’s immune system to proteins that are carrying cancer-typical alterations. Physicians and cancer researchers from Heidelberg and Mannheim have now treated adult patients with advanced midline gliomas, difficult-to-treat brain tumors, with a peptide vaccine for the first time. The vaccine mimicked a mutational […]

22

Sep , 2023
the future of mRNA vaccine analysis and quality assurance?
Tag: DNA

the future of mRNA vaccine analysis and quality assurance?

In a recent study published in Nature Communications, researchers proposed a simplified approach for analyzing messenger ribonucleic acid (mRNA) vaccines using long-read sequencing. Study: mRNA vaccine quality analysis using RNA sequencing. Image Credit: Jo Panuwat D/Shutterstock.comBackground Messenger RNA vaccines demonstrated safety and efficacy during the COVID-19 pandemic, but extensive quality and purity testing is required […]

5

Sep , 2023
How is next-generation protein sequencing democratizing protein sequencing?
Tag: DNA

How is next-generation protein sequencing democratizing protein sequencing?

What challenges do researchers usually encounter with conventional proteomic methods? The proteomics field is highly complex, spanning initial biological samples to comprehensive analysis. An overarching theme repeatedly emphasized by researchers revolves around the absence of a universal solution for this entire process. Rather, each phase demands meticulous harmonization. Researchers often find themselves at a crossroads. They must […]

29

Aug , 2023
Researchers unravel structure of MCM8/9 enzyme linked to infertility and cancer
Tag: DNA

Researchers unravel structure of MCM8/9 enzyme linked to infertility and cancer

Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this. For 15 years, Trakselis has been interested in the MCM8/9 enzyme. Part of the minichromosome […]

19

Aug , 2023
RARα receptor plays unexpected role in T cell activation
Tag: DNA

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd-;but very important-;to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha (RARα), is known to control gene expression programs in the nucleus, but it also now appears to operate outside the […]
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