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Study reveals impact of hybrid immunity and booster vaccination on antibody waning

In a recent study published in npj Vaccines, researchers conducted a systematic literature review and meta-analysis to examine the decline in neutralizing antibody (nAb) titers following COVID-19 vaccination. The study systematically reviewed the evidence of antibody waning within the first six months after receiving the last dose of the primary COVID-19 vaccination compared to booster […]

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New insights into why obesity puts individuals at risk for severe influenza

In a recent study published in the journal Nature Communications, researchers used blood and airway sampling of morbidly obese individuals and murine models to elucidate the mechanisms underpinning severe cases of influenza among the obese population. Study: Obesity dysregulates the pulmonary antiviral immune response. Image Credit: Jarun Ontakrai/Shutterstock.com Background Their findings reveal that obesity induces deficits in […]

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Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

A recent study published in the journal Science discussed variant-adapted boosters for coronavirus disease 2019 (COVID-19). Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have decreased the burden of the COVID-19 pandemic. Nevertheless, the waning of neutralizing antibodies (nAbs) and the emergence of variants of concern (VOCs) have reduced the efficacy of vaccines, prompting […]

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Breast milk microbiome changes after COVID-19 vaccination, linked to enhanced infant protection

In a recent study published in the journal npj Vaccines, researchers investigated whether the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger ribonucleic acid (mRNA) vaccine could alter the breast milk microbiome and ways in which the changes impact breast milk antibody titers. Vaccine-induced antibodies in breast milk confer immunity to newborns against SARS-CoV-2. However, […]

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Why are most Americans skipping the COVID-19 booster?

In a recent study published in the journal Vaccine, researchers investigated why more than 80% of eligible Americans have not taken their severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) vaccine booster dose. They conducted an online survey of 2,298 respondents to evaluate the reasons underlying the low observed response. Their results elucidate that, despite consistent […]

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Could baseline gut microbiota and metabolome help predict the durability of immune responses elicited by different COVID-19 vaccines?

In a prospective longitudinal study published in the Journal of Signal Transduction and Targeted Therapy, researchers characterized the gut microbiota composition associated with the durability of coronavirus disease 2019 (COVID-19) vaccine-induced immunity. Additionally, they determined the impact of COVID-19 vaccines on long-term gut microbiota changes. To this end, they created two groups comprising people vaccinated with CoronaVac […]

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BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

In a recent article published in Jama Network Open, researchers estimated the association between receipt of BNT162b2 vaccine and coronavirus disease 2019 (COVID-19)-related ambulatory visits in United States (US) children below the age of five years. Study: Receipt of BNT162b2 Vaccine and COVID-19 Ambulatory Visits in US Children Younger Than 5 Years. Image Credit: Ground Picture/Shutterstock.com Background In the […]

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Is there an association between the COVID-19 pandemic and cancer incidence?

A recent JAMA Network Open study assessed whether the coronavirus disease 2019 (COVID-19) pandemic, caused by the transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), influenced cancer incidence in Manitoba, Canada. Study: New Cancer Diagnoses Before and During the COVID-19 Pandemic. Image Credit: Stokkete/Shutterstock.com Background The ongoing COVID-19 pandemic has massively impacted the global healthcare system. This pandemic […]

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